Early gestational diabetes mellitus risk predictor using neural network with NearMiss.

DOI码：

10.1080/09513590.2025.2470317

所属单位：

Xiamen University, First Affiliated Hospital

发表刊物：

Gynecological Endocrinology

刊物所在地：

Italy

关键字：

"Gestational diabetes mellitus";"NearMiss; logistic regression";"neural network algorithms"

摘要：

Background: Gestational diabetes mellitus (GDM) is globally recognized as a significant pregnancy-related condition, contributing to complex complications for both mothers and infants. Traditional glucose tolerance tests lack the ability to identify the risk of GDM in early pregnancy, hindering effective prevention and timely intervention during the initial stages. Objective: The primary objective of this study is to pinpoint potential risk factors for GDM and develop an early GDM risk prediction model using neural networks to facilitate GDM screening in early pregnancy. Methods: Initially, we employed statistical tests and models, including univariate and multivariate logistic regression, to identify 14 potential risk factors. Subsequently, we applied various resampling techniques alongside a multi-layer perceptron (MLP). Finally, we evaluated and compared the classification performances of the constructed models using various metric indicators. Results: As a result, we identified several factors in early pregnancy significantly associated with GDM (p < 0.05), including BMI, age of menarche, age, higher education, folic acid supplementation, family history of diabetes mellitus, HGB, WBC, PLT, Scr, HBsAg, ALT, ALB, and TBIL. Employing the multivariate logistic model as the baseline achieved an accuracy and AUC of 0.777. In comparison, the MLP-based model using NearMiss exhibited strong predictive performance, achieving scores of 0.943 in AUC and 0.884 in accuracy. Conclusions: In this study, we proposed an innovative interpretable early GDM risk prediction model based on MLP. This model is designed to offer assistance in estimating the risk of GDM in early pregnancy, enabling proactive prevention and timely intervention

第一作者：

Min Zhao

合写作者：

Xiaojie Su,Lihong Huang

论文类型：

Original Research

文献类型：

Journal Article

卷号：

41

期号：

1

ISSN号：

0951-3590

是否译文：

否

发表时间：

2025-02-24